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Definition Box Signal Peptide: A short peptide sequence that triggers downstream cellular responses (gene expression, enzyme activation, cytokine release) by interacting with receptors or transport proteins rather than by being incorporated into larger structures

Epilogue A large number of studies have provided evidence of an increased fungal load, along with an altered mycobiome population, in the tumor microenvironment, suggesting fungal involvement in carcinogenesis

doi: 10.1038/s41585-023-00747-w 167 ZaffaroniNBerettaGL

Anal Chim Acta 720:112117 Blechinger J, Herrmann R, Kiener D, Garcia-Garcia FJ, Scheu C, Reller A, Brauchle C (2010) Perylene-labeled silica nanoparticles: synthesis and characterization of three novel silica nanoparticle species for live-cell imaging

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Oral wins on convenience and lack of injection risk but has the weakest bioavailability rationale for a peptide of this size