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(Nature, 2004) reported that T4 improves cardiomyocyte survival and post-infarction cardiac function in murine models, with an anti-fibrotic effect

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It was first described as methionine dependence of tumors in rats and later as inability of cancer cells to survive and grow in a culture medium, in which LMet was replaced with its immediate precursor LHcy [2, 8, 26, 27]

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