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Its approval was supported by the Phase III ARCADIA clinical trial program, which included more than 1,700 patients and found that Nemluvio given every four weeks led to significant improvements in skin clearance versus placebo
The extended half-life also enables study of long-term GH elevation effects without the confounding variable of repeated daily injections
A 2021 review in Obesity Reviews found that patients taking weight-promoting medications alongside GLP-1s had significantly reduced weight loss compared to those not taking these drugs