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ROS and RNS production are facilitated by pattern recognition receptors [C-reactive protein (CRP), toll-like receptors] capable of recognizing pathogen (bacterial/viral)-associated molecular patterns and/or damage-associated molecular patterns in apoptotic or damaged cells (92100) (Figure 6)

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Importantly, these levels were still lower than those reported in the non-inducible liver-specific Gclc KO mouse strain 30

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doi: 10.3389/fncel.2014.00315

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