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Interestingly, LPC-O 18:0 and SM t39:0 showed significant differential expression not only between patients with RA and OA, but also between patients with OA and HC

"As GLP-1 receptor agonist medications become increasingly integrated into the care of patients undergoing body contouring, our findings suggest that these drugs may have subtle effects on wound healing, even if they don't increase overall surgical risks," Koenig said in a statement

These include situations where metformin is ineffective, contraindicated, or when patients fail to reach their target glycemic control despite treatment with metformin and other medications