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As a side problem, the overuse and misuse of these lifesaving drugs have developed the top global public health crisis named antibiotic resistance occurring worldwide (Akram et al., 2023)

NAC supplementation raises blood glutathione levels by 30-35% within two weeks of consistent daily intake at 600mg twice daily

RMD Open 7 , e001735 (2021)

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46 APAP can freely cross the selective maternal-fetal barrier of the placenta, after which it can then be metabolized by fetal hepatocytes, causing fetal hepatic necrosis if appropriate therapy with NAC is not administered in a timely manner