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In a diabetic mouse model, it reduced oxidative stress-induced neuropathy by triggering antioxidative defense signals (Agca et al

ACHIEVE-2 (NCT06192108) A comparator trial evaluating orforglipron versus dapagliflozin (an SGLT-2 inhibitor) in adults with type 2 diabetes

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The lymph fluid of mice has higher levels of glutathione and oleic acid, and less free iron compared to plasma

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