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Multiple meta-analyses and pooled analyses of the published literature have found that low-protein diets and very-low-protein diets supplemented with nitrogen-free derivatives of essential amino acids (eg, compounds called keto-analogues or keto acids) have a range of benefits in slowing disease progression

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Importantly, existing drug resistance mechanisms that challenge treatment of infections like Staphylococcus aureus do not confer resistance to TrxR targeting compounds

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doi: 10.3390/ani11061627 12 BarcelosS