Genomic Regulation: It resets the gene expression of the Ubiquitin-Proteasome System (UPS), enhancing the cell's ability to clear toxic proteins (upregulating 41 UPS genes)
It belongs to a class of medications called central nervous system (CNS) stimulants
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An apple a day to prevent cancer formation: Reducing cancer risk with flavonoids
For example, genetic screens have been performed to identify mutations that either enhance or suppress the Glp or tumorous phenotypes produced by partial loss-of-function and gain-of-function alleles of glp-1 (Kodoyianni et al., 1992
GST non-enzymatic functions GSTs are also implicated as modulators of signal transduction pathways implicated in cell survival and apoptosis, where they control the activity of members of the mitogen-activated protein kinase (MAPK) family 24,25
