34 , 396407.e6 (2022)
Under baseline conditions, the renal clearance of L-carnitine (13 mL/min) is substantially less than glomerular filtration rate (GFR), indicating extensive (9899%) tubular reabsorption
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High-dose intravenous protocols (up to 50 mg/kg daily, ~3,500 mg for a 70 kg person) have been used safely in patients with metabolic disorders [8] , indicating a wide therapeutic margin