In one study, the clearance of free valproate was decreased by 50% in 7 patients with cirrhosis and by 16% in 4 patients with acute hepatitis, compared with 6 healthy subjects
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FOLIC ACID requirements are far greater in athletic performance horses where the synthesis and absorption from the gut are reduced by the stress of training and performance
Targeting fungal-specific biological pathways, such as chitin synthesis or virulence factor secretion, offers opportunities for designing highly selective and less toxic agents (Zhu et al., 2023)
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Analyses used SAS version 9.3 mixed-effects regression models to estimate the effect and effect size of the treatment (Laird and Ware, a priori hypothesis that the change in the metabolic biomarker was greater for participants who underwent treatment as compared with the placebo group
