A rigorous 2026 UK review Read the full review Neuroscience 1 May 2026 Dihexa for Chemo Brain (CICI): The 2026 UK Cancer Survivor Cognitive Recovery Review Can a synaptogenic peptide help chemo brain
In 1981, for example, a paper published in the International Journal of Clinical Pharmacology, Therapy, and Toxicology described a trial with six volunteers who experienced immediate sleep pressure after intravenous DSIP infusion, as well as increased sleep time, decreased sleep onset, and better sleep efficiency without any sedative effects.13 Three years later, two other human trials across ten test subjects with insomnia found that DSIP administration yielded statistically significant improvements in several key sleep measures fewer sleep arousals, greater sleep efficiency, and increased REM, spindle, and slow-wave sleep.14 The above studies had shortcomings, namely their very small sample sizes, but the sleep-improving effects in cases of insomnia point to DSIPs potential to live up to its name
In 2024 a research group in Iran did a well designed and controlled trial comparing 5cc of placental derived exosomes with 5cc of normal saline
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Kacheva S, Kolk K, Morgenthaler NG, Brabant G, Karges W
