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We refer readers to the publicly available measure specifications to determine details on diagnosis codes for denominators, as these specifications provide comprehensive information about the specific codes and definitions used for each measure

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The severity of symptoms can also differ

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For example, some release only tryptase, and others only chymase (both along with histamine, IL-6, TNF-alpha, prostaglandins, etc.).[ref] Allergens and pathogens cross-link with IgE and activate mast cells