Decreasing waist circumference with stable or increasing limb measurements suggests favorable fat loss with lean mass preservation
Careful dose escalation, patient education (e.g., smaller meals, slower eating, avoiding highfat foods during titration), and proactive management of nausea and constipation can mitigate these effects and support adherence
Anscher, N.E
J Pharmacol Exp Ther 287(2):773778 Okada K, Shoda J, Taguchi K, Maher JM, Ishizaki K, Inoue Y, Ohtsuki M, Goto N, Takeda K, Utsunomiya H, Oda K, Warabi E, Ishii T, Osaka K, Hyodo I, Yamamoto M (2008) Ursodeoxycholic acid stimulates Nrf2-mediated hepatocellular transport, detoxification, and antioxidative stress systems in mice
Lee MS, Lin RY, Chang YT, et al
If you take a capsule 20 minutes before training, it may not even be fully absorbed when you start your session