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10 Additionally, GLP1 RA use has notable challenges: frequent gastrointestinal side effects, risk for nutritional deficiencies, muscle and bone loss, high costs and limited accessibility

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Another consequence of this shift is the changing role of clinical expertise

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Patients treated with semaglutide, a glucagon-like peptide-1 receptor agonist (GLP-1RA) approved for treating type 2 diabetes (T2D) and for weight management have reported reduced desire to drink and smoke