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Another oral alpha-synuclein aggregation inhibitor, Anle138b [112], showed favourable safety and pharmacokinetics in a phase 1 trial (NCT04208152) [113]

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The authors followed a series of 500 subjects (56% men

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GLP-1R mediated effects on visceral illness Much debate exists around whether the suppression of feeding induced by GLP-1 and GLP-1 mimetics is solely a homeostatic effect