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Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression

The market for weight-loss drugs is projected to be worth around US$130 billion by 2030, which would require an annual growth of nearly 50% from todays levels

Small-molecule activators of ATF6 are being developed to enhance ER folding capacity, stimulate ERAD, and reduce ER stress, with potential benefits in heart failure and ischemic cardiomyopathy

The hexosamine biosynthetic pathway couples growth factor-induced glutamine uptake to glucose metabolism

Plant sources often require combining (rice with beans, for instance) to achieve completeness

The effects depend on individual deficiency levels and lifestyle