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A significant reduction in the activity of DHAR was observed in whole leaf extract at all time points

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However, it should be measured in the morning after fasting to avoid fluctuations in Tyr levels as these may increase during the day due to Tyr intake

Therefore, timing with meals is irrelevant as it doesnt face degradation from stomach acid or enzymes

The role of iNOS in IBD is further complicated by its relationship with cytokines and pro-inflammatory cytokines, which upregulate iNOS expression (140)