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Furthermore, it suggests that hypothalamic-pituitary autoimmunity may be triggered by infectious events, as occurs in LC, and lead to hormonal deficiencies (59)

When studied together, they trigger a larger cellular response than the sum of their individual effects

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These transgenerational effects operate primarily through epigenetic modifications, germline transmission of molecular alterations, and persistent fertility impairments that challenge traditional concepts of toxicological risk assessment (84)

J Basic Clin Physiol Pharm 2014

Roger Truscott, Universities of Sydney and Wollongong, Australia