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Usually youre not wanting to eat because youre too nauseous or your stomach is already upset or uneasy, and so it doesnt do anything with the true hunger producing hormone, so the moment that you get off, Ive heard from a lot of patients, their hunger and their cravings come back with a vengeance, Sadler says

[131] also investigated the effects of these two substances in combination

It sounds a cautionary note for short-term use without a more comprehensive approach to weight management. Overeating far more likely Adam Collins, associate professor of nutrition at the University of Surrey in England, who was not involved in the study, called the paper timely and important. Collins underlined that weight regain is a common issue in all weight loss interventions, but the paper shows that this problem is amplified with GLP-1 medications

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