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Gastrointestinal Function
Ma W, Heianza Y, Huang T, Wang T, Sun D, Zheng Y, et al
It has been shown that certain medications at toxic doses such as paracetamol deplete glutathione
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185 Besides, other MTHFD2 inhibitors have been reported, including DS18561882 and LY345899 in a substrate-based manner, and treatments based on them decrease cellular NADPH/NADP + ratio, increase cellular ROS levels, and impair tumorigenesis and metastasis
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