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pylori: Helicobacter pylori HCC: Hepatocellular carcinoma HBV: Hepatitis B virus HBx: HBV X protein PINK1: PTEN-induced putative kinase 1 MMP: Matrix metalloproteinase Nrf2: Nuclear factor erythroid 2-related factor 2 GPX4: Glutathione peroxidase 4 LMPt: Miriplatin-loaded liposomes POLG: Polymerase gamma EMT: Epithelial-mesenchymal transition RCC: Renal cell carcinoma VHL: Von Hippel-Lindau OTA: Ochratoxin A Pb: Lead CDDO: 2-Cyano-3,12-dioxooleana-1,9(11)-dien-28-oic acid References Spinelli JB, Haigis MC