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Wegovy follows a more gradual escalation pattern, starting at 0.25 mg and increasing monthly through 0.5 mg, 1.0 mg, 1.7 mg, to a maintenance dose of 2.4 mg weekly

doi: 10.31744/einstein_journal/2023RC0628

The latter, while providing valuable real-world signals, are inherently susceptible to confounding by indication and selection bias, as patient characteristics and co-morbidities may differ significantly between treatment groups