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Increased levels of active xanthine oxidase (XO) were detected in maternal plasma, placenta, and umbilical cord blood in cases of GDM, probably because inflammatory cytokines could enhance the production and activity of XO [24]

They conclude that a larger study population is necessary to evaluate rapid-acting insulin efficacy in this population better

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Additionally, gut microbiota enhances resistance to Streptococcus pneumoniae pneumonia and Klebsiella pneumoniae pneumonia via nucleotide-binding oligomerization domain protein 2 (NOD2) and granulocyte-macrophage colony-stimulating factor (GM-CSF) signaling pathways (52)

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