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The systemic nature of these peptide mechanisms means they could potentially address both skin and joint manifestations of psoriatic disease

Macrophage Recruitment The peptide also acts as a chemoattractant for macrophages, particularly the M2 polarization associated with the proliferative phase of repair

Van Konynenburg, RA (April 21, 2012)

Bile acids BAs act as pleiotropic signaling molecules that regulate intestinal homeostasis by integrating metabolic, epithelial, and immune pathways through receptor-mediated mechanisms

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