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GLP-1R agonists appear to perform favorably compared with other approved pharmacological agents for pediatric obesity

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Thats below Wegovy pills 16.6% in OASIS 4, but orforglipron also demonstrated significant improvements across key cardiometabolic risk factors, and the convenience advantage may outweigh the efficacy gap for many patients and payers

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384:989-1002) enrolled 1,961 adults with BMI 30 or 27 with weight-related comorbidities

While more research is needed to fully understand the relationship between semaglutide and gut microbiota, these findings suggest that semaglutide may have a beneficial effect on gut health