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The nitroalkylation process occurs and in vivo, is involved in redox processes and cell signaling through the reversible covalent bound and post-traslational modifications responsible for structure, function and subcellular distribution of proteins (Valdez et al., 2011) and regulating the pro-inflammatory effect of oxidant exposure (Nair et al., 2007)

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Consider incorporating the following: Caloric targets: Many plans recommend 12001500 calories/day, as advised by a licensed healthcare provider

The fact that we found reduction at the end of 4th week during 4-week intermittent fasting and then 73-fold increase in PRKCSH GP level 1 week after 4-week intermittent fasting is suggestive of increased autophagy during 4-week intermittent fasting and decreased autophagy with the subjects return to ad libitum eating (Table 2)

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*Correspondence: Bin Feng, [email protected] Wu, [email protected] These authors have contributed equally to this work This article was submitted to Food Chemistry, a section of the journal Frontiers in Nutrition Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers