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The FDA continues to monitor these medications and has resolved previous shortages, making them more available to patients who need them

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84 In contrast, MPTP treatment reduces TH-positive neurons, decreases concentrations of dopamine as well as its metabolites 3,4-dihydroxyphenylacetic acid and homovanillic acid, and increases the ratio of dopamine metabolites to dopamine

doi:10.1530/ERC-13-0545

It varies from person to person