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The mechanisms by which LA reduces liver fat content in HFD animals may be related to suppressing oxidative stress and lipid peroxidation, improving mitochondrial dysfunction, inhibiting insulin resistance, and regulating some related factors or genes (such as ROS-scavenging enzyme genes) to inhibit excessive fat synthesis in the liver

Second, we did not perform adequate histological examination due to patients severe hypoxemia

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If you require extended prednisone use, your healthcare team may recommend holding GLP-1 initiation until prednisone can be reduced, or they may optimize your GLP-1 dose specifically for prednisone co-treatment

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