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Biochemical Journal

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Efficacy, safety, and cost of Goeckerman therapy compared with biologics in the treatment of moderate to severe psoriasis

Typically, top biomarker candidates identified from screening studies will be validated through a combination of secondary focused screens and individual gene perturbation studies which include independent sgRNAs, rescue experiments, and functional assayssuch as proliferation, apoptosis, or immune cell co-cultureto confirm their role in tumor biology

M., Alomari S., Tyler B