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In randomized controlled trials, GLP-1 RAs reduce systolic blood pressure by approximately 1 to 2 mm Hg, with lesser effects on diastolic blood pressure [62]

Purpose-built for physicians GLP-1-based medications reduce body weight in type 1 diabetes in real-world setting Key takeaways: Adults with overweight and type 1 diabetes using liraglutide, semaglutide or tirzepatide achieved significant weight loss at 1 year

However, its short action duration necessitates frequent injections [97]

In these cases, supplementation has been linked to improvements in muscle function and exercise performance

The Prescription Requirement You cannot walk into a Canadian pharmacy and buy a GLP-1 medication over the counter

This is an excellent illustration of my current weekly video series on pharmacy benefit transparency