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Forward-Looking Statements This article reflects information available in July 2026

Encouraged by these results, Novo Nordisk launched the much larger SOUL trial the following year

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The studies in vivo indicated that the GEN-loaded star-shaped copolymer mannitol-functionalized nanoparticles were able to show significantly superior antitumor activity than the linear copolymer mannitol-functionalized nanoparticles and pristine GEN (Wu et al., 2016)