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Upon transfection or transduction with genes encoding for one or multiple drug metabolizing enzyme genes, HepG2 cells have been shown to be a valuable model system to study the role of bioactivating enzymes in the cytotoxicity of toxicants (Vignati et al., 2005

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doi: 10.3390/molecules25214891 158 BaeJYKimJIParkSYooKKimIHJooWet al

Les maladies neurodgnratives acclres, comme la maladie de Parkinson et la maladie dAlzheimer, prsentent des niveaux levs de dommages dus au stress oxydatif au cerveau et des niveaux faibles de glutathion