trt and semaglutide reddit 9 Months on Tirzepatide : r/Testosterone Can Testosterone Replacement Therapy Help

Key Takeaway: Spironolactone is a multi-purpose medication used for blood pressure, fluid management, and hormonal balance, primarily by acting as a potassium-sparing diuretic

UTI is not listed as a common adverse event in Ozempic's FDA labeling, but patient reports and clinical observations suggest GLP-1 medications may increase risk through dehydration and metabolic changes

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Regular communication with your medical provider during this transition is vital

Pharmacol Rev (2016) 68(4):9541013

That said, the Wegovy HD 7.2mg dose (approved March 2026) produced 20.7% in the STEP UP trial, which puts it very close to tirzepatide territory