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Ideal candidates are those with a high BMI, comorbid conditions such as type 2 diabetes, and an elevated cardiovascular risk profile

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doi: 10.1007/s10803-004-5283-1 69

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Its design illustrates a radical peptidomimetic : only two amino acid residues (Tyr-Ile) are preserved from the native peptide, flanked by non-peptide acyl chains to cross biological barriers