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Melatonin inhibits LPS-induced NO production in rat endothelial cells

In contrast, well-known enterocyte marker genes such as FABP2, APOA4, RBP2 , and ANPEP showed expression across various intestinal cell types, with the exception for APOA4 (Supplementary Fig

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This has the potential to improve the design and implementation of clinical trials, as well as the evaluation of treatment effectiveness

Overall, these findings highlight the critical role of phenolic-rich formulations in enhancing antioxidant defense, particularly within functional food products designed to mitigate oxidative stress