Djonlagic I et al
The timeline for a final determination has not been specified
GI comfort and exercise timing Intense exercise during the nausea window (first 12 to 24 hours post-injection) is uncomfortable at normal drug levels and potentially worse after an early dose
In a smaller cohort of patients with more severe CD phenotypes, including 17% with perianal involvement and 24% with penetrating or fistulizing disease, numerical reductions across outcomes were observed in the GLP-1RA group, but these differences did not reach statistical significance (104)
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Hall ME, Faha M, Cohen JB, Ard JD, Egan BM, Hall JE, Lavie CJ, Ma J, Ndumele CE, Schauer PR, Shimbo D, on behalf of the American Heart Association Council on Hypertension