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Semaglutide microdosing has grown in popularity among individuals who want a gentler, slower introduction to therapy especially those who are sensitive to gastrointestinal side effects or who benefit from smaller, more gradual dose changes

Theres some evidence that coming off of semaglutide more gradually might be a better option for weight maintenance, and a recent study found that gradually tapering off semaglutide may help prevent weight regain

The drug is generally administered orally and is taken once a day before food

The STEP-1 trial, one of the landmark studies for semaglutide 2.4mg, showed that participants lost approximately 9.7% of their lean mass alongside a 19.3% reduction in fat mass

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Understanding what these medications actually are and how they work can help you make a more informed decision about your weight loss treatment