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Los efectos significativos generalmente requieren 12-16 semanas de tratamiento para prdida de peso y aproximadamente 3 meses para estabilizacin del control glucmico

The mechanism is not stupid

10.1016/j.cell.2011.10.026 Cell 83 MollerN.JorgensenJ

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The prevalence of obesity and its cardiovascular com- plications have increased substantially in recent decades to involve younger demographics, with over 340 million children and adolescents aged 519 diagnosed as over- weight or obese as of 2016 [1]

Simultaneously, obesity and IR amplify the risk of complications by increasing the likelihood of gestational diabetes mellitus and pregnancy-induced hypertension (33, 34)