It is also suggested that women with endometriosis due to genetic mutations, over respond to estrogen which encourages growth of the lesions, while progesterone receptors are being silenced and becoming unresponsive to progesterone, which would normally balance out the strong influence of estrogen
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The results of certain in vivo studies from this program were presented at ObesityWeek 2021, highlighting the promising effects observed following treatment with VK2735 and other compounds from the series