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By interfering with this binding, it induces apoptosis of senescent cells and promotes their clearance

Increased plasma bilirubin typically is classified as primarily indirect (an approximation of unconjugated bilirubin) or direct (an approximation of the sum of conjugated bilirubin and biliprotein)

This makes it valuable for patients with documented deficiencies, malabsorption syndromes (e.g., Crohns disease, postbariatric surgery), or acute medical needs such as severe thiamine deficiency

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