Patients who switched from semaglutide to orforglipron maintained a mean 79.3% of their body weight reduction compared with the placebo arm which maintained a mean 37.6% of their weight loss
GLP-1s Didnt Affect the Risk of Wet AMD In people who already had dry AMD, taking a GLP-1 didnt slow progression to wet AMD, says Young
10.1038/nn.3202 26 DixitT
In brief, endocannabinoids, oxytocin, neuropeptide Y (NPY), peptide YY (PYY), cholecystokinin (CCK), vasoactive intestinal peptide (VIP), and galanin may play a role in TBC regulation (Table 1) [102075119121131134138139140141143144145146147148149150151152153154155156157158159160161162163164]
They might have low appetite and trouble meeting their nutritional needs, or trouble controlling their blood sugar
Reuters reporting described the FDA proposal as an effort to curb risky mass compounding now that branded GLP-1 drugs are widely available in regular channels