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doi: 10.1001/jama.2019.2941 84 WenSNguyenTGongMYuanXWangCJinJet al

In addition, TR-12@LGMN immunization elicited strong tumor-specific immune responses, such as infiltration of effecter memory T cells and antigen-specific CTLs, offering lasting tumor immunity as well as synergizing with PD-1 blockade in enhanced therapeutic efficacy

It has achieved -cell function preservation, meaningful reduction of albuminuria and significant improvements of several components of the MS [46, 47]