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Adequate levels can: Improve white blood cell function Increase resistance to infections Reduce inflammation and support overall immunity 5

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Studies of polycystic ovary syndrome (PCOS) have revealed the role of PPM1K in complex diseases: PPM1K knockout mice exhibit PCOS-like phenotypes, including elevated BCAA levels, increased androgen levels, and ovarian dysfunction (111)

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injections of 100 nmol kg 1 GLP-1MK-801 ( n = 8 mice), 10 nmol kg 1 semaglutide ( n = 8 mice) or vehicle (isotonic saline, n = 7 mice) for 5 days with daily measurements of running distance at the time of injection