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On the other hand, certain studies have demonstrated the overexpression of GLP-1R in brain tumors, embryonic tumors, gut and lung neuroendocrine tumors, including other endocrine tumors like Pheochromocytomas, raising concerns that existing GLP-1RAs can contribute to tumor growth in humans (Shilyansky et al., 2025

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(1) Some peptides communicate directly with the brain or endocrine system, while others affect the immune or digestive systems

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Youll need your plan contract number, certificate number, plan sponsor (employer/organization), your personal details and address, and the patients details (if different from the plan member), including relationship and contact information

There are no clear published guidelines for management of skin pigmentation despite some clinical trials of shorter duration and small sample sizes