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However, semaglutide has proven cardiovascular benefit (SELECT), 7+ years of safety data, oral formulation options, and established availability

Compounded medications are prepared by specialized compounding pharmacies and fall outside the discount card networks

Head-to-head comparison The cleanest comparison so far is SURPASS-2, which pitted tirzepatide against semaglutide 1 mg in adults with type 2 diabetes (not the obesity dose, but still the most rigorous head-to-head we have)

For women with obesity, excess weight often disrupts hormonal balance and ovulation