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Accordingly, the use of semaglutide in severe gastroparesis is contraindicated, and expert panels advise baseline gastric motility assessment in patients with pre-existing motility disorders (Wegovy Prescribing Information)

Thats partly because it acts on two gut hormone pathways instead of one

Additionally, temperature fluctuations can reduce its effectiveness, making it less effective at controlling blood sugar or aiding in weight loss

The oral format concerns molecules chosen for compatibility

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Several newer medications, mainly GLP-1 receptor agonists, have been introduced