Paracetamol plus TRAIL sensitizes primary murine and human LSEC death in a Bim- and caspase-dependent manner Our in vitro results with both human endothelial cell lines strongly indicate that TRAIL synergizes with paracetamol in killing endothelial cells
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Since it has been shown that deficiency affects the expression of different genes in the liver, including NO-like actions that raise cGMP through elevated guanylate cyclase, biotin exerts a secondary role in controlling gene expression (147)
39 In addition, deep learning-based image analysis was applied to histopathological scoring variables for quantifying whole-section number of lipid-laden hepatocytes (% of hepatocytes with lipids droplets), number of inflammatory foci (foci per mm 2 ), hepatocyte ballooning index (cells/mm 2 ) as well as proportionate (%) area of perisinusoidal and periportal fibrosis, respectively
