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Data Availability Statement The data presented in this study are available upon request from the corresponding author.

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Both semaglutide and tirzepatide were placed on the FDA's official drug shortage list by 2022, products from two of the world's largest pharmaceutical companies that collectively could not manufacture enough supply to meet what their own commercial teams, and the clinical data, had told them would be a large market

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Additionally, all included studies were RCTs, thereby reducing within-trial bias

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