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Pharmacokinetics (ADME) Absorption Well absorbed orally Rapid onset Distribution Highly protein bound (~99%) Metabolism Mainly hepatic metabolism Glucuronidation is significant Half-life About 23 hours But effect lasts longer due to enzyme inhibition Excretion Mainly via bile/feces Some renal excretion --- 5

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Nanoparticle conjugation and pulmonary delivery enhance the protective efficacy of Ag85B and CpG against tuberculosis

doi: 10.3390/plants9070809 171 ReiterRJRosales-CorralSTanDXJouMJGalanoAXuB

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